Profile Of SGPT (Serum Glutamic Pyruvic Transaminase) Levels In Active Smokers Aged 20-60 Years

Authors

  • Dimas Taufiqur Rohman Sudarwo Universitas dr. Soebandi Jember
  • Sholihatil Hidayati
  • Ahdiah Imroatul M

DOI:

https://doi.org/10.36858/jmid.v2i1.20

Keywords:

SGPT levels, Smoker, 20-60 years old

Abstract

Background: Cigarettes are one of the main risk factors for several chronic diseases that can result in death. This shows that cigarettes are a big problem for public health.

Purpose: to determine the SGPT (Serum Glutamic Pyruvic Transaminase) level profile in active smokers aged 20-60 years

Methods: This research is quantitative. The population in this study is active smoking patients at the Grand Raya Husada Clinic, Pandanarum Village, Lumajang Regency, which totals 60 active smoking patients. The data analysis technique used in this study is descriptive.

Results: The results of laboratory examinations showed that serum SGPT (Serum Glutamic Pyruvic Transaminase) levels in 60 respondents showed that 55 respondents (91.67%) had normal SGPT levels. As many as 5 respondents (8.33%) showed high or abnormal SGPT levels.

Conclusions: Normal SGPT levels in smokers aged 20-60 years were 91.67%, and high or abnormal SGPT levels were 8.33%.

References

Parmar MP, Kaur M, Bhavanam S, Mulaka GSR, Ishfaq L, Vempati R, et al. A Systematic Review of the Effects of Smoking on the Cardiovascular System and General Health. Cureus. 2023;15(4).

Cha SR, Jang J, Park SM, Ryu SM, Cho SJ, Yang SR. Cigarette Smoke-Induced Respiratory Response: Insights into Cellular Processes and Biomarkers. Antioxidants. 2023;12(6).

Klabunde M, Collado D, Bohon C. How people think about the chemicals in cigarette smoke: A systematic review. J Psychiatr Res. 2017;94(3):36–46.

World Health Organization. Gats|Global Adult Tobacco Survey Fact Sheet Indonesia 2021 Gats Objectives. Fact Sheet Indonesia. 2021. 1–2 p.

Badan Pusat Statistik Jawa Timur. Persentase Penduduk Usia 15 Tahun Ke Atas yang Merokok dalam Sebulan Terakhir Menurut Kabupaten / Kota dan Kelompok Umur di Provinsi Jawa Timur , 2021 Percentage of People Aged 15 Years and Above Who are Smoking During a Month Prior to The Survey by Regen. Badan Pusat Statistik Jawa Timur. 2021.

Holipah H, Sulistomo HW, Maharani A. Tobacco smoking and risk of all-cause mortality in Indonesia. PLoS One [Internet]. 2020;15(12 December):1–12. Available from: http://dx.doi.org/10.1371/journal.pone.0242558

Rutledge SM, Asgharpour A. Smoking and liver disease. Gastroenterol Hepatol. 2020;16(12):617–25.

Battah KA, Darwish ;, Badran H, Shraideh ZA, Battah KA;, Badran DH&, et al. Effect of Cigarette Smoking on the Structure of Hepatocytes: TEM Study Efecto del Tabaquismo Sobre la Estructura de los Hepatocitos: Estudio MET. Int J Morphol. 2016;34(4):1239–44.

Elisia I, Lam V, Cho B, Hay M, Li MY, Yeung M, et al. The effect of smoking on chronic inflammation, immune function and blood cell composition. Sci Rep [Internet]. 2020;10(1):1–16. Available from: https://doi.org/10.1038/s41598-020-76556-7

Saulahirwan R, Sinay H, Karuwal RL. Transaminase Enzyme and Liver Histopatological Structure of Mice Facing to Smoke Cigarettes After Administerred with Enhalus acoroides Peel Extract. Biosaintifika. 2023;15(1):97–104.

Lestari D, Prasetyorini T, Widayanti G. Increased Serum Aminotransferase Levels for Active Smokers Effect To Degree of Smoking (a Library Research). Proceeding Int Conf Syedza Saintika. 2021;1(1).

Prambudi H, Supenah P, Ikhwani I. Gambaran Kadar Serum Glutamic Pyruvic Transaminase (Sgpt) pada Perokok Aktif di Kabupaten Cirebon. J Multidisiplin Indones. 2023;2(1):89–94.

Tanoeisan AP, Mewo YM, Kaligis SHM. Gambaran Kadar Serum Glutamic Pyruvic Transaminase (Sgpt) Pada Perokok Aktif Usia > 40 Tahun. J e-Biomedik. 2016;4(1).

HR HN, Tjiptaningrum A, Karrima N. Dampak Asap Rokok Terhadap Kadar Sgpt. J Penelit Perawat Prof. 2024;6(5):2191–6.

Wijaya BA, Sari Mariyati Dewi Nataprawira. Effect of Degree of Smoking Based on Brinkman Index on Hemoglobin Levels in Adults. Community Med Educ J. 2024;5(2):525–31.

Sunita R. Lamanya Paparan Karbon Monoksida Terhadap Profil Enzim Alanin Aminotranferase. J Nurs Public Heal. 2018;6(1):76–81.

Kim SJ, Oh HS, Cha YS, Kim MY, Kim H. Evaluation of hepatic injury in acute carbon monoxide-poisoned patients in emergency department. Hum Exp Toxicol. 2020;39(7):883–9.

Caliri AW, Tommasi S, Besaratinia A. Relationships among smoking, oxidative stress, inflammation, macromolecular damage, and cancer. Mutat Res. 2021;787:1–49.

Downloads

Published

2024-06-30

How to Cite

Sudarwo, D. T. R., Sholihatil Hidayati, & Ahdiah Imroatul M. (2024). Profile Of SGPT (Serum Glutamic Pyruvic Transaminase) Levels In Active Smokers Aged 20-60 Years. Journal of Medical Laboratory in Infectious and Degenerative Diseases, 2(1), 15–19. https://doi.org/10.36858/jmid.v2i1.20

Issue

Section

Articles